Databases & Tools

HuMemProtDB is a curated, searchable relational database of human membrane proteins, covering integral, peripheral, and lipid-anchored membrane proteins.

Available analytical functions include:
1) Membrane protein analysis
2) Structural analysis
3) Subcellular localization analysis
4) Functional and biomarker analysis

iHPDM is an in-silico human proteome digestion resource containing a comprehensive peptide database generated from neXtProt human proteins and isoforms using 15 single- and dual-protease combinations. It supports protease selection and comparison in shotgun proteomics, facilitating the investigation of missing proteins, protein isoforms, and single amino acid variant peptides.

MinProtMaxVP is a combinatorial optimization approach based on the Set Cover Problem. It generates a minimized set of SAV-containing protein sequences while preserving all possible variant peptides for proteogenomic database searching.

gDecoy is a web-based computational tool for generating decoy sequence databases for protein- and peptide-level target-decoy searches. It supports multiple decoy-generation strategies, including reverse, pseudo-reverse, and pseudo-shuffle approaches, with enzyme-specific generation of decoy peptides from in-silico digested sequences.